Current research - Therapeutics

Research from our Irish Research Council funded PhD project on cell death mechanisms in novel anti-cancer compounds - Copper (II), Manganese (II) and Silver (I) complexes containing dicarboxylate and 1,10-Phenanthroline ligands - was recently published in BioMetals.

Read more about this study here:

O’Sullivan, E., O’Shea, D., Devereux, M., Howe O., Apoptotic cell death induced by copper (II), manganese (II) and silver (I) complexes containing bridging dicarboxylate and 1,10-phenanthroline ligands: one of the multi-modes of anticancer activity?. Biometals 38, 785–805 (2025). https://doi.org/10.1007/s10534-025-00676-8