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Glucosidase for novel glycoside synthesis

In this laboratory, we discovered, cloned, and expressed, an exceptionally robust Glucosidase enzyme (β-glucosidase from Streptomyces griseus (SgBgl)) [Kumar, 2017]. Preliminary experiments showed that this enzyme could synthesise certain alkyl glucosides (biodegradable detergent made from glucose and alcohols) with unusually high yield, under mild conditions, in the presence of DES (unpublished). This exciting finding opens a host of possibilities for Green Chemistry applications. Our preliminary studies show that this enzyme can be developed into a broadly useful biocatalyst by appropriate modification. Such a catalyst will have broad applications in research and industry.  Glycoside synthesis will be used as a proof-of-concept study.

min. 2.1 BSc in a Biological Science

Scholarship not available. Fees & Materials to be paid by the student. Materials costs are very significant

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Supervisor

Dr Gemma Kinsella

Award Level

PhD

Mode of Study

Full Time

Deadline to Submit Applications

Open Call