This foundational module will provide learners with a general introduction to the molecular biology principles upon which cells depend. Key concepts such as nucleic acid structure and function, and chromosomal organisation will be learned. The role nucleic acids play in cellular processes will be explored, from replication during cellular division to gene expression, and how these processes are regulated. The core fundamentals behind genetics will be explored, through inheritance patterns such as mendelian inheritance, and how inherited traits translate to the phenotype of an individual.
|Structure and function of nucleic acids.
Cellular macrostructures (e.g. nucleosome, ribosome).
DNA replication and the cellular machinery involved
DNA repair mechanisms
The molecular process of transcription.
The molecular process of translation.
Control of gene expression at the cellular level.
Eukaryotic chromosomal organisation.
Basic patterns of inheritance (e.g. Mendelian, X-linked).
Molecular basis of inheritance of traits.
The fundamental link between genotype and phenotype.
Isolation of nucliec acids from variety of sample sources
Lectures, tutorials and laboratory practical classes; in-class quizzes/puzzles; videos/animations; online learning; peer learning using web-enabled and in-class student response systems; self-directed learning.
|Module Content & Assessment