This module aims to provide the student with a knowledge and understanding of current and integrated review of metabolism and metabolic regulation. Key areas covered in this module include; Energy in the Body, the Production and use of Adenosine Tri-Phosphate (ATP); Glycolysis, the Krebs Cycle, the structure the cell membrane and membrane transport systems; the structure and function of cellular lipids, carbohydrates and vitamins, and a knowledge of the sources of cellular energy within the human body. Students will learn how the body copes with extreme situations, such as disease or exercise, and appreciate how the human body adapts to many different conditions. Furthermore, it is the aim of this module to provide the student with an appreciation of the role of functional biochemistry in the diagnosis, treatment, monitoring and maintenance of health.
Energy: In the Body, Tissues and Biochemical Processes
Energy Transformations in the Whole Body - Fuel Stores, Energy Intake and Expenditure; Energy Transformations in Tissues and Organs; Energy Transformation in Biochemical Reactions and Pathways - Gibbs Free Energy, Steady State Condition and Equilibrium; Adenosine Triphosphate(ATP)-It's Role in the Cell.
What is metabolic regulation?; What makes one tissue different from another?; movement of substances across membranes; Rapid changes in metabolic flux and how they are achieved; longer term control of metabolic pathways;
Coordination of whole body metabolism
Communication between tissues; What connects the tissues?; hormones and their receptors; hormones and short-term control on enzyme activity; hormones and their longer-term control of enzyme activity; steroid and thyroid hormones.
Metabolism for extreme situation: Health and Disease
Metabolic response to tissue injury, and the effects of inflammation, infection and trauma;
Metabolic Regulation in Sport and Exercise
Principles of metabolic regulation; High-intensity exercise; Endurance exercise; High-intensity intermittent exercise.
Methods used to achieve the module learning outcomes will include lectures, tutorials, laboratory practicals, interpretation of data, case studies, problem-solving exercises, video presentations, self-directed learning and computer-based learning
|Module Content & Assessment