This module will introduce learners to the concepts of clinical chemistry tests and their relevance to clinical diagnostics. They will develop their knowledge and understanding about biochemical changes in disease and learn practical techniques in clinical chemistry. The learner will begin to relate the results provided by the clinical laboratory to clinical signs and symptoms of underlying biochemical and physiological phenomena.
- The role of the Clinical Chemistry Lab
- Reference ranges and what is normal- Interpretation of laboratory tests
- Identify pre-analytical, analytical and post-analytical errors that affect laboratory tests
- Critical care analytes:- e.g. Glucose, Calcium Sodium/Potassium
- Lipid & lipoproteins:
- Metabolic analytes and panels
- Endocrine disorders – e.g. Thyroid, Diabetes Mellitus
- Proteins – investigation of total proteins, albumin and globulins disorders
- Enzymology - Principles of assay of clinically significant enzymes and their quantitative use as markers of cell/tissue damage
- Automation and clinical information systems
- Establishing control interval and reference ranges,
- Renal function tests
- Cardiac markers
- Lipid analysis
- Protein analysis
- Bone profile tests
- Plasma enzymes
- Carbohydrate tests
The module will use a mixture of didactic lectures (24h) and either laboratory sessions (TU867 & TU866) or workshops (TU870) or a mixture, depending on the programme (22h). Simulated diagnostic specimens and reports with defined biochemical abnormalities will be using during practical training/workshops. Attendance at laboratory sessions is mandatory.
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