Aimed at addressing the strong commercialisation focus in the current research environment, this assignment-based module provides students with a detailed understanding of the theory of biosensor or bio-product development from conception to prototype. Emphasis will be placed on application of the information obtained in the lecture program into a theoretical design of a biosensor/bio-product.
Module aim
To provide theoretical knowledge of biosensor/bio-product design and to develop practical application of methodologies for biosensor/bio-product design.
Biomaterials
Introduction to biomaterials, molecule-surface interactions, Surface modification, Surface characterisation, Biomaterials for biosensors and diagnostic devices
Signal Transducers
Principles and examples of optical signal transducers e.g. fluorescence, SPR, electrical signal transducers e.g. pententiometric, voltrammetric, impedance & other signal transducers e.g. microbalances
Instrumentation
Review of a wide range of sensors and instrumentation from electrochemical to optical applications. Sensor outputs through the use of signal processing and analogue circuit concepts
Biomolecules used for sensing
Enzymes, antibodies, proteins/peptide receptors, Nucleic Acids, whole cells. General requirements and considerations for immobilisation, Immobilisation techniques e.g. covalent and physical
Diagnostics
Design and assay planning, method development and pre-study validation, devices for point of care applications, kit manufacture (with series of examples), problems often encountered and remedies.
Marketing and selling.
Pitching product, basic market research techniques
Module duration is one academic year. The contact hours for this module will be delivered within the first semester of the year and student self-directed learning will be facilitated on-line in semester 2 to facilitate work placements.
Module Content & Assessment | |
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Assessment Breakdown | % |
Other Assessment(s) | 100 |