Module Overview

Haematology 1

This module will investigate the aetiology and pathophysiology of a selection of haematological diseases and bleeding/thrombotic disorders. Students will explore key concepts in the principles of current and emerging diagnostics and will review the application and interpretation of these strategies in the diagnosis, monitoring and treatment of these conditions. The importance of point of care testing in Haematology will also be reviewed.

The CORU Standards of Proficiency covered in this module include Domain 5 Professional Knowledge and Skills; P6 , P15, P16 & P23

Module Code

BIOL 4090

ECTS Credits

5

*Curricular information is subject to change

Lecture Programme;

  • Review the pathophysiology and current/emerging laboratory diagnostics and treatments of a selection of red cell and bleeding/thrombotic disorders
  • General Haematology; Anaemia of chronic disease, Haemolytic anaemias, Nutritional anaemias, Haemochromatosis and iron overload disorders, Haematology in infectious disease – e.g. Malaria, COVID19;
  • Bone marrow failure syndromes; Congenital bone marrow failure syndromes; Aplastic anaemia, Paroxysmal Nocturnal haemoglobinuria;
  • Haemoglobinopathies; Sickle cell, Thalassaemia and other Haemoglobin variants;
  • Haemostasis and Thrombosis; Bleeding disorders; Haemophilia, Von Willebrand’s disease, Inherited Thrombophilias, Acquired conditions – Antiphospholipid Syndrome, Heparin induced thrombocytopenia, Inherited and acquired platelet disorders including Immune Thrombocytopenia, Rare coagulation disorders, Microangiopathic anaemias: Disseminated intravascular coagulation, Thrombotic Thrombocytopenic purpura, Haemolytic uraemic syndrome. Point of care testing;
  • Special Interest Haematology; Obstetric Haematology, Paediatric Haematology.

Practical Programme;

  • Case-based laboratory investigation of a selection of red cell and haemostatic disorders;
  • Techniques employed include blood film preparation and review, flow cytometry, rapid diagnostic tests, molecular diagnostics, special coagulation testing and platelet function assessments;
  • Interpretation and communication of laboratory diagnostics in the clinical assessment, monitoring and treatment of haematological diseases and bleeding/thrombotic disorders

Lectures, tutorials and case study based practical classes

Module Content & Assessment
Assessment Breakdown %
Other Assessment(s)100