This module will focus on the aetiology and pathophysiology of haematological malignancies. Current and advancing practice in the diagnosis, monitoring and treatment of a variety of myeloid and lymphoid diseases will be discussed.
The CORU Standards of Proficiency covered in this module include Domain 5 Professional Knowledge and Skills; P30 & P31
*Curricular information is subject to change
Lecture Programme;
- Review of the pathophysiology and current/emerging laboratory diagnostics and treatments of a selection of haematological malignancies;
- Haematopoiesis; Detailed investigation into proliferation, differentiation, maturation and regulation of haematopoietic stem cells in the bone marrow;
- Haematological Malignancies; Myelodysplastic Neoplasms, Acute Leukaemia Chronic Leukaemia, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Plasma cell disorders, Myeloproliferative Neoplasms;
- Therapies; Chemotherapy; Radiotherapy; Stem cell transplantation; CAR-T cell therapy; Antibody therapy; Pathway Inhibitors;
Practical and Workshop Programme;
- The principle and application of laboratory tests which aid in the diagnosis, classification and monitoring of haematological malignancies; blood film and bone marrow microscopy, immunophenotyping, chromosomal abnormalities and molecular analysis;
- Evidence based critical skills workshops.
Lectures (18 hr), tutorials (4 hr), case study based practical classes (5 hr) / workshops (13 hr)
| Module Content & Assessment | |
|---|---|
| Assessment Breakdown | % |
| Formal Examination | 60 |
| Other Assessment(s) | 40 |