Module Overview

Medical Microbiology 2: Microbial Pathogenesis and Infection Control

This module will focus on the multi-factorial nature of microbial pathogenesis and current and advancing practice in the detection, treatment and control of infectious disease. The module will explore the expanding pathogenic disease models and new developments in antimicrobial treatment and multidrug resistance. Best practice in infection prevention and control, and epidemiological investigation of healthcare- and community-associated infection will also be reviewed.

Module Code

BIOL 4227

ECTS Credits


*Curricular information is subject to change

Lecture Programme

Antibiotics: therapeutic properties, modes of action, susceptibility test guidelines and methods,

New developments in antimicrobial design and alternative treatment strategies

Antimicrobial resistance: emergence, acquisition, mechanism, laboratory detection and control strategies for antimicrobial multi-drug, extreme-drug and pan-drug resistant pathogens including MRSA, PNSP, VRE, ESBL-producers and CPO

Microbial Virulence Models: Emergence of new evolving pathogens, Microbial adaptation during chronic infection, Bacterial toxins Bacterial biofilm formation and treatment of biofilm infections 

Healthcare and Community-associated Infection: incidence, modes of transmission of infection, best practice in infection control and prevention strategies, role of the microbial diagnostics surveillance, epidemiological investigation of healthcare and community- associated infections.

Practical Programme

Antimicrobial susceptibility testing- EUCAST Disc diffusion, Agar dilution and E-test MIC Screening and confirmatory testing for MDRO

Infection Control Workshop: molecular epidemiological typing and outbreak investigation

Evidence-based Critical Skills workshops: evaluate the importance of patient population, sample size, sample sites, control samples, reference method, performance data and statistical evaluation in study design, assay validation and data interpretation

The CORU Standards of Proficiency covered in this module include:

Domain 5. Professional knowledge and skills: P30 & P31

Lectures 16, Tutorials 6, Laboratory Teaching Sessions 5, Workshops 13

Module Content & Assessment
Assessment Breakdown %
Formal Examination60
Other Assessment(s)40