This module is delivered in semester 2 and builds upon prior learning in module CHEM1005. The module objective is to further the understanding of introductory topics in general and organic chemistry. Topics such as thermochemistry, electrochemistry and solution equilibria will be introduced and expanded upon as well as stereochemistry (optical isomerism), the physical properties and reactivity of alkynes, benzene and derivatives, alcohols, amines, carbonyl containing compounds (aldehydes, ketones, carboxylic acids and their derivatives) and the mechanisms for halogenation of methane and electrophilic addition reactions of alkenes. This module will be advantageous for those students interested in a more advanced study of chemistry and biochemistry. The laboratory element is designed to reinforce the lecture material.
General chemistry: Thermochemistry, First Law, work of expansion, heat, calorimetry, enthalpy, Hess’ Law. Electrochemical reactions, voltaic cells, electrochem series fuel cells. Equilibrium – concept, Kc, Ksp, Kw, pH scale calculating [H+ ] and [OH- ], Henderson Hasselbalch Equation
Organic chemistry: Introduction to reaction mechanisms – mechanism for free radical halogenations and for electrophilic addition (Markovnikov’s rule). Chemistry, physical properties, reactions, applications and IUPAC nomenclature of alkynes and simple aromatic compounds. Functional group chemistry, IUPAC nomenclature, physical properties, applications and reactions of compounds containing each of the following functional groups: alcohols, aldehydes, ketones, carboxylic acids and derivatives, amines and derivatives and haloalkanes. Optical isomers - polarimeter, chirality, enantiomers (one chiral centre only) and racemic mixture. Biological significance of optical isomerism.
Laboratory Programme: The following practicals (or an appropriate alternative) will be carried out.
o Thin Layer Chromatography analysis of analgesic drugs
o Preparation of soap (or an alternative reflux set-up)
o Chemistry of the alcohols and the aldehydes and ketones
o Revision session for laboratory exam (titrations and cation tests)
o Determination of heats of neutralisation
o Preparing a buffer solution
o Laboratory Exam
Students will learn through lectures that incorporate student learning activities, online learning resources (including pre-lecture resources and online quizzes and homework), tutorials (in the form of problem solving workshops) and laboratory practicals. Self directed learning is encouraged using tutorial questions and on-line resources and quizzes
| Module Content & Assessment | |
|---|---|
| Assessment Breakdown | % |
| Formal Examination | 45 |
| Other Assessment(s) | 55 |