The purpose of this module is to provide the learner with a detailed understanding of specific areas of spectroscopy in particular physical and organic spectroscopy. The physical spectroscopy element consists of a more advanced treatment of rotational, vibrational and electronic spectra with particular emphasis on the origin and underlying principles. The theoretical aspects are underpinned by suitably chosen experiments which amplify and reinforce the lecture material.
The organic spectroscopy element consists of mass spectrometry, IR, 1H NMR and 13C NMR. A particular focus will be placed on integrated problem solving. The laboratory element will involve integrated problem solving workshops for structure elucidation.
Rotational spectroscopy: Non-rigid rotor model. Determination of bond lengths and dipole moments. Vibrational spectroscopy: Anharmonic oscillator model. Isotope and kinetic isotope effects. Polyatomic molecules: overtones and combination bands. Electronic transitions in polyatomic molecules. Radiative and non-radiative decay processes.
Mass spectrometry, instrumentation, molecular ion, isotopes. High resolution mass spectra, fragmentation patterns, Mc Lafferty rearrangements.
Proton NMR spectroscopy: Spin-spin splitting patterns, coupling constant and correlation with structure, non-first order spectra, interpretation of spectra.
Carbon-13 NMR spectroscopy: Interpretation (including DEPT spectra).
Integrated problem solving: Use of UV/vis, IR, mass, proton and carbon NMR spectra in the elucidation of the structures of organic compounds.
Laboratory work is sourced from the School of Chemical and Pharmaceutical Sciences Laboratory Manual.
This module is delivered through lectures and laboratory classes.
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