The purpose of this module is to develop the student's practical skills in Drug Formulation, Organic chemistry, Biochemistry and Pharmaceutical Analysis as well as their scientific communication skills
Introduction to Chromatography
Introduction to basic instrumentation and theory of GC and LC analysis as used in the pharmaceutical industry
Organic Chemistry
Prepare simple drug-type compounds, purify organic compounds using recrystallisation and distillation; work with low temperature reactions and reaction control; separate mixtures of compounds using acid/base chemistry and liquid extraction; perform compound characterisation using melting point, TLC, and IR spectroscopy; measure optical activity using polarimetry.
Principles of Biochemistry
Application of the Beer-Lambert Law using the Biuret Assay and the Warburg-Christian Assay; Isolation of glycogen from cells and glycogen estimation using the Glucose oxidase assay; Determination of enzyme activity and preparation of a Michaelis-Menten Curve and Lineweaver-Burke plot for a model enzyme system; Protein analysis using SDS-PAGE.
Drug Formulation
Formulation practical 1: milling and blending;Formulation practical II: granulating, drying, tableting; Preparation of a cream, an ointment, a gel, a suspension;Testing of tablets: dissolution; disintegration; hardness; friabilityPreparation and testing of capsules
Scientific Communications
Introduction to scientific journal publications; Citation and referencing methods; Report writing including drafting meeting minutes; Effective oral presentation skills. Computer based data analysis and creation of scientific graphs.
| Module Content & Assessment | |
|---|---|
| Assessment Breakdown | % |
| Other Assessment(s) | 100 |