This module covers clinical pharmacology and the pathophysiological mechanism of drug action.
The aim of this module is to deepen student knowledge in relation to the pharmacology of drugs used to treat
the most common pathological conditions which occur in the field of clinical physiology and to outline how these
drugs could impact on clinical measurement methods. Also, Students gain experience to enhance their team
working and communication skills.
It is delivered to fourth year students on the B.Sc. in Clinical Measurement Science and is aimed at an
intermediate level of understanding for the clinical application of pharmacology.
Indicative syllabus covered in the module and / or in its discrete elements
Pathophysiology of ischaemic heart disease and mechanism of action of anti-clotting agents, ACE inhibitors and antianginal medications in management of this condition. Relationship of the proposed mechanism of action of these agents to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Pathophysiology of cardiac arrhythmias and the role of class 1, class 2, class 3 and class 4 anti-arrhythmic agents in management of this. Relationship of mechanism of action of these agents to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Pathophysiology of hypertension and mechanism of action of anti-hypertensives (diuretics, vasodilators, beta- blockers and ACE inhibitors. Relationship of mechanism of action of these agents to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Pathophysiology of heart failure and the role of cardiac medications ( cardiac glycosides, diuretics, beta blockers, organic nitrate) in prophylaxis of this. Relationship of mechanism of action of these agents to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Pathophysiology of thromboembolic disease and the pharmacological management of this (anticoagulants, antiplatet and thrombolytic medications). Relationship of mechanism of action of these agents to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Pathophysiology of asthma (in relationship to event triggers) and the mechanism of action of bronchodilators and steroids in management and treatment of this condition. Relationship of mechanism of action of these agents to patient side effects and possible implications for clinical measurement methods and clinical physiology practice
Pathophysiology of other conditions of respiratory system and mechanism of action of therapeutic interventions with special consideration given to inhalation delivery devices.
. Pathophysiology of atherosclerosis and hyperlipidemia and the mechanism of action of lipid lowering drugs and lifestyle management in prophylaxis of this. Relationship of mechanism of action of lipid lowering drugs to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Proposed pathophysiology of epilepsy and mechanism of action of most commonly prescribed Antiepileptic medications. Relationship of this mechanism of action to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Proposed pathophysiology of depression (uni and bipolar) and mechanism of action of SSRI, MOAI, TCA and mood stabilisers. Relationship of mechanism of action of these medications to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Proposed pathophysiology of anxiety and anxiety states and mechanism of action of most commonly prescribed anxiolytic medications. Relationship of this mechanism of action to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Proposed pathophysiology of schizophrenia and mechanism of action of neuroleptic medications. Relationship of this mechanism of action to patient side effects and possible implications for clinical measurement methods and clinical physiology practice.
Proposed pathophysiology of Parkinsons disease and mechanism of action of medications in management of this. Relationship of this mechanism of action to side effects and implications for clinical measurement methods and clinical physiology practice.
Proposed pathophysiology of Alzheimers disease and mechanism of action of medications in management of this. Relationship of this mechanism of action to side effects and implications for clinical measurement methods and clinical physiology practice.
Proposed physiology of substance addiction and implications of this for clinical measurement methods and clinical physiology practice.
Lectures with class discussion
Independent learning with development of written report/poster presentation based on specific drug therapy and clinical condition relevant to clinical physiology major discipline choice.
| Module Content & Assessment | |
|---|---|
| Assessment Breakdown | % |
| Formal Examination | 60 |
| Other Assessment(s) | 40 |