This module will introduce students to the fundamentals of pharmaceutical microbiology such as microbial growth and control, infection, and contaminants. Furthermore, sterile manufacturing in the pharmaceutical industry and healthcare will be covered.
Microbial groups significant to the pharmaceutical industry: as causative agents of disease, contaminants, and producers of pharmaceutical products, Bacterial toxins, Bacterial Genetics
Microbial products: introduction to antibiotics and Antibiotic-resistant
Health Care Associated Infections (HCAI): Major Health Care-Associated Infections, Factors determining HCAI, Most common HAI infectious agent, Sources, Routes of infection and Prevention
Categories of pharmaceutical products I: sterile products. Categories of pharmaceutical products II: non-sterile products.
Sterilisation methods used in the pharmaceutical industry: Control of microbial growth, Biological Indicators, Steam sterilisation (autoclaving), Dry Heating, Ethylene Oxide (ETO), Gamma or Electron radiation, Filtration.
Contamination control in the manufacturing environment (Environmental Monitoring): personal, structural and operational hygiene, environmental monitoring methods: settle plates, active air samplers, surface sampling, personnel monitoring.
Pharmaceutical water system: Types of water used in pharmaceutical manufacturing, water system contamination, Design and control of water system, Monitoring water system: Sampling, Testing and reporting.
Standard analytical methods used in pharmaceutical microbiology. Relevant standards.
Laboratory Practical:
Bacterial groups
Environmental monitoring: air and surface contamination.
Assessment of water contamination
Clean room Garbing
- Face to face in class lecture
- Synchronous and Asynchronous lectures
- Laboratory work associated with the lecture
- Tutorial
- Audio-visual’s technology
| Module Content & Assessment | |
|---|---|
| Assessment Breakdown | % |
| Formal Examination | 40 |
| Other Assessment(s) | 60 |