Lecturer in Medical Genetics

Email: fergus.x.ryan@tudublin.ie

Tel: (01) 220 5534

Biography

Dr Fergus Ryan graduated with a PhD in molecular genetics in 1991 and performed research as a postdoctoral scientist in UCD on the role of inhibin in bovine fertility. He then moved to Harvard Medical School researching the regulation of gene expression by the thyroid hormone receptor. In 1995 he took up a position in the National Centre for Medical Genetics in Our Lady’s Hospital for Sick Children, setting up genetics testing for many common genetic diseases in Ireland. He has been a permanent lecturer in medical genetics in DIT since 1998 and has supervised the work of 22 postgraduate students since then.

Qualifications

 BSc, PhD  

Research Themes

Novel mutation detection technologies, gene regulation

Keywords

HPV, real time mutation detection

Key Publications

Eustace Ryan, S., Ryan, F., O’Dwyer, V., Neylan, D. (2016) A real time ARMS PCR / high resolution melt curve assay for the detection of the 3 primary mitochondrial mutations in Leber's hereditary optic neuropathy. Mol. Vis. 2016; 22:1169-1175

O'Grady D, Kenny K, Power S, Egan J, Ryan F. (2016) Detection of Yersinia enterocolitica serotype O:9 in the faeces of cattle with false positive reactions in serological tests for brucellosis in Ireland. Vet J. 2016 Oct;216:133-5.

Eustace Ryan, S., Ryan, F., Barton, D., O’Dwyer, V., Neylan, D. (2015) Development and validation of a novel PCR-RFLP based method for the detection of the 3 primary mitochondrial mutations in Leber's hereditary optic neuropathy patients. Eye and Vision 2015, 2:18  doi:10.1186/s40662-015-0028-0

Professional Memberships

• Active member of the Academy of Clinical Science and Laboratory Medicine (ACSLM)

• Active member of the Irish Molecular Diagnostics Network (IMDN)

External Activities/Outreach

• External examiner - Honours BSc in Biotechnology, Athlone Institute of Technology

• Frontiers Molecular Diagnostics” Editorial Board

• Guest Lecturer in Bioinformatics MSc in Health Informatics, TCD

Research and Academic Interests

Research interests include the development of novel real time mutation detection technologies in human and animal genetic disorders, detection of pathogenic organisms using molecular techniques, analysis of HPV gene expression and the analysis of polymorphism effects on thrombosis and foetal development.