This module will introduce the learner to bioenergetics and the metabolism of carbohydrates and lipids in terms of both structure and pathways.
Bioenergetics is the study of the transformation of energy in living organisms and the goal of bioenergetics is to describe how living organisms acquire and transform energy in order to perform biological work.
Structural Biochemistry:
This part of the lecture series will outline the structure and function of carbohydrate molecules such as glucose, sucrose, starch and glycogen. It will also explain how lipids are classified and outline the structure and function in the body of lipid molecules such as fatty acids, triacylglycerols, phospholipids, sphingolipids and cholesterol.
Bioenergetics and metabolism:
This section of the lecture series will describe the concept of bioenergetics and investigate energy transformations in the body. Metabolism will also be introduced and interplay between the metabolic pathways and pathway bioenergetics will be highlighted. The key role of enzymes and their regulation in the metabolic pathways is covered. A detailed review of various metabolic pathways including glycolysis (aerobic and anerobic), citric acid cycle and the electron transport chain are also covered. Through the module the impact of metabolic disorders on these pathways will be highlighted
Laboratory Programme :
The practical series may include but is not limited to;
- Measurement of sucrose solution
- Glucose determination in serum samples
- Rate of glucose released from Hela cells
- Anaerobic metabolism of glucose
- Regulation of pyruvate dehydrogenase activity
- Citrate synthase activity in citric acid cycle
Structural Biochemistry
This part of the lecture series will outline the structure and function of carbohydrate molecules such as glucose, sucrose, starch and glycogen. It will also explain how lipids are classified and outline the structure and function in the body of lipid molecules such as fatty acids, triacylglycerols, phospholipids, sphingolipids and cholesterol.
Bioenergetics and metabolism
This section of the lecture series will describe the concept of bioenergetics and investigate energy transformations in the body. Metabolism will also be introduced and interplay between the metabolic pathways and pathway bioenergetics will be highlighted. The key role of enzymes and their regulation in the metabolic pathways is covered. A detailed review of various metabolic pathways including glycolysis (aerobic and anerobic), citric acid cycle and the electron transport chain are also covered. Through the module the impact of metabolic disorders on these pathways will be highlighted.
Laboratory Programme
The practical series may include but is not limited to; Measurement of sucrose solution Glucose determination in serum samples Rate of glucose released from Hela cells Anaerobic metabolism of glucose Regulation of pyruvate dehydrogenase activity Citrate synthase activity in citric acid cycle
Students will learn through lectures, tutorials and laboratory practicals and workshops.
| Module Content & Assessment | |
|---|---|
| Assessment Breakdown | % |
| Formal Examination | 60 |
| Other Assessment(s) | 40 |