The aim of this module is to provide students with comprehensive theoretical knowledge of microbial pathogens that are of major significance to public health. This will include a detailed understanding of the spread of microorganisms, disease causation mechanisms, diagnosis and/or treatment of infections caused by bacterial, viral and parasitic eukaryotic pathogens. The module places particular emphasis on understanding practical methods, both existing and emerging, relevant to current clinical laboratory practice.
Lecture Programme
Virulence: key virulence factors that promote bacterial colonisation (including adhesion to host cells) and cause damage to the host (including bacterial toxins and their function). Microbial secretion systems and biofilms in disease pathogenesis
Pathogenesis and host interaction: molecular mechanisms of infection and disease caused by clinically significant bacterial, viral and parasitic agents e.g. H. pylori, Salmonella, Pseudomonas, Influenza, Malaria.
Future challenges in pathogenesis of infectious diseases, e.g. Bordetella pertussis
Surveillance and Diagnostics: Molecular detection methods of selected pathogens including nucleic acid amplification tests, in situ hybridisation assays, MLST and MALDI-TOF MS. Use of novel technologies and robotics in microbial diagnostics and laboratory automation
The module theory content will be primarily delivered through lectures. Teaching methods will incorporate online learning resources, tutorials, discussion, readings and self-directed learning.
| Module Content & Assessment | |
|---|---|
| Assessment Breakdown | % |
| Formal Examination | 60 |
| Other Assessment(s) | 40 |