Module Overview

Advances in Cellular Pathology and Clinical Cytology

The aim of this module is to provide detailed knowledge of current practice and future trends in Cellular Pathology and Clinical Cytology. Recent developments in the National Cancer Strategy, Cancer Screening programmes, and novel diagnostic, prognostic and therapeutic cancer biomarkers will be reviewed.

Module Code

BIOL 9231

ECTS Credits

10

*Curricular information is subject to change

Overview of National Cancer Control Programme and National Cancer Strategy.Recent developments and reviews of cancer screening programmes in Ireland and Europe.Review of Dissection practice and its role in tumour staging, diagnosis and cancer biobanking.Classification and diagnostic algorithms of carcinomas, adenocarcinomas, melanoma, lymphoma, sarcomas.Update on targeted therapies including tyrosine kinase inhibitors, angiogenesis blocking and immune cell modulators.Review of biomarker analysis methods for tumour investigation, including immunocytochemistry, ISH, gene expression profiling and next generation sequencing.Gene expression profiling and gene mutation analysis for DNA, mRNA, microRNA alterations of significance in patient therapy and prognosis. Current trends in screening, diagnostic, predictive and therapeutic biomarkers of selected cancers of cervix, breast, lung, colon, stomach, brain, soft tissue and lymphoid organs. Quality issues in Cellular Pathology relating to specimen management, dissection, immunostaining and molecular analyses.Models of disease – int eractive student sessions investigating epidemiology, aetiology and diagnosis of selected cancer models related to the Irish population.

Lectures, tutorials, student presentations, and workshops.Student directed learning

Module Content & Assessment
Assessment Breakdown %
Formal Examination60
Other Assessment(s)40