This module aims to provide an insight into the bioinformatics tools available for the acquisition and analysis of DNA, RNA and protein sequences and to evaluate the use of these tools in the biomedical and biotechnology arenas. Students will learn the skills required to access nucleic acid sequences and to design tests for the detection of mutations / alterations in those sequences.
The module also aims to familiarize students with the construction of a database using statistical software (PASW) and to evaluate and apply this statistical software (PASW) in the analyses and presentation of biomedical data. In addition, students will learn to interpret and critically evaluate the
output from the statistical analyses of data.
Indicative syllabus covered in the module and / or in its discrete elements;
The structure of the human genome
The structure of eukaryotic and prokaryotic genes
NCBI, ENSEMBL and UCSC genome databases
PCR Primer design software
Bioinformatics requirements for PCR, RT-PCR, qPCR
Application of bioinformatics resources for the design of diagnostic tests
PASW statistical software
The appropriate use and interpretation of statistics in the analyses of data
Descriptive and inferential statistical analyses of data of biomedical and biotechnological interest
Statistical methods for the exploration of association, agreement, changes and differences in databases
Lectures / tutorials
Computer laboratory workshops
Student-directed reading and on-line education.
| Module Content & Assessment | |
|---|---|
| Assessment Breakdown | % |
| Other Assessment(s) | 100 |