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Research Output

MOSAIC Clinical Trial Methods 

McCrann S, Flitcroft I, Strang NC, et al. Myopia Outcome Study of Atropine in Children (MOSAIC): an investigator-led, double-masked, placebo-controlled, randomised clinical trial protocol. HRB Open Res. 2019;2:15. Published 2019 Jul 23. doi:10.12688/hrbopenres.12914.1 

 

Is the Optometry Profession Ready for Myopia Control? 

McCrann S, Flitcroft I, Loughman J. Is optometry ready for myopia control? Education and other barriers to the treatment of myopia. HRB Open Research 2019,2:30 

 

Association between Zinc and Myopia in US Children and Adolescents 

Burke N, Butler JS, Flitcroft DI, McCartney D, Loughman J. Association of Total Zinc Intake with Myopia in US Children and Adolescents. Optometry and Vision Science. 2019;96:647-54. doi:10.1097/OPX.0000000000001418 

 

Parental Attitudes to Myopia 

McCrann S, Flitcroft DI, Lalor K, Bush A, Loughman J. Parental attitudes to myopia: A key agent of change for myopia control? Ophthalmic & Physiol Opt 2018; 38: 298–308. DOI: 10.1111/opo.12455 

 

Analysis of Syndromic Forms of Myopia Reveals Novel Myopia Genes and Pathways 

Flitcroft DI, Loughman J, Wildsoet CF, Williams C, Guggenheim JA, for the CREAM Consortium. Novel Myopia Genes and Pathways Identified From Syndromic Forms of Myopia. Investigative Ophthalmology & Visual Science. 2018;59(1):338-348. doi:10.1167/iovs.17-22173. 

 

CHAMP – UK Atropine Trial Methods 

Azuara-Blanco A, Logan N, Strang N, Saunders K, Allen PM, Weir R, Doherty P, Adams C, Gardner E, Hogg R, McFarland M, Preston J, Verghis R, Loughman J, Flitcroft DI, Mackey DA,Sze-Yee Lee S, Hammond C, Congdon N, Clarke M. Low-dose (0.01%) atropine eye-drops to reduce progression of myopia in children: a multicentre placebo-controlled randomised trial in the UK (CHAMP-UK)—study protocol. Br J Ophthalmol 2019;0:1–6. doi: 10.1136/bjophthalmol-2019-314819. 

 

Retinal, Optical and Environmental Factors in Myopia 

The complex interactions of retinal, optical and environmental factors in myopia aetiology Flitcroft DI. Progress in retinal and eye research (2012) 31 (6), 622-660. 

 

Western Australia Atropine for the Treatment of Myopia (WA‐ATOM) study - Methods 

Lee SSY, Mackey DA, Lingham G, Crew JM, Chen FK, Charng J, Fletcher N, Flitcroft DI, Loughman J et al. Western Australia Atropine for the Treatment of Myopia (WA‐ATOM) study: Rationale, methodology and participant baseline characteristics. Clin Experiment Ophthalmol. 2020; 1– 11. Doi.org/10.1111/ceo.13736 

 

Serum zinc levels and myopia 

Burke, N., Butler, J.S., Flitcroft, I. and Loughman, J., The relationship between serum zinc levels and myopia. Clin Exp Optom. (2020) doi:10.1111/cxo.13069 https://arrow.tudublin.ie/otpomart/81/ 

 

Smartphone use and myopia 

McCrann S, Loughman J, Butler JS, Paudel N, Flitcroft DI. Smartphone use as a possible risk factor for myopia. Clin Exp Optom. 2020. DOI:10.1111/cxo.13092 

 

Choroidal Thickness Profiles and Associated Factors in Myopic Children 

Kobia-Acquah E, Flitcroft DI, Lingham G, Paudel N, Loughman J. Choroidal Thickness Profiles and Associated Factors in Myopic Children. Optom Vis Sci. 2023 Jan 1;100(1):57-66. 

 

Systematic review of clinical practice guidelines for uveitis 

Ghadiri N, Reekie IR, Gordon I, Safi S, Lingham G, Evans JR, Keel S. Systematic review of clinical practice guidelines for uveitis. BMJ open ophthalmology. 2023;8(1) 

 

Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging. Ophthalmology. 

Chan E, Chong EW, Lee SS-Y, Franchina M, Yazar S, Eastwood P, McArdle N, Mackey DA, Lingham G. Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging. Ophthalmology. 2023;130(4):445-448 

 

 

Impact of the digital environment on the ocular surface. Ocular Surface 

Wolffsohn JS, Lingham G, Downie LE, Huntjens B, Inomata T, Jivraj S, Kobia-Acquah E, Muntz A, Mohamed-Noriega K, Plainis S, Read M, Sayegh RR, Singh S, Utheim TP, Craig JP. TFOS Lifestyle: Impact of the digital environment on the ocular surface. Ocular Surface. 2023;28:213-252 

 

Evidence quality report: Advancing the evaluation and synthesis of research evidence. Ocular Surface 

Downie LE, Britten-Jones AC, Hogg RE, Jalbert I, Li T, Lingham G, Liu S-H, Qureshi R, Saldanha IJ, Singh S, Craig JP. TFOS Lifestyle - Evidence quality report: Advancing the evaluation and synthesis of research evidence. Ocular Surface. 2023;28:200-212 

 

Myopia outcome study of atropine in children: Two-year result of daily 0.01% atropine in a European population 

Loughman J, Kobia-Acquah E, Lingham G, Butler J, Loskutova E, Mackey DA, Lee SSY, Flitcroft DI. Myopia outcome study of atropine in children: Two-year result of daily 0.01% atropine in a European population. Acta Ophthalmologica. 2023 [Online ahead of print]. 

 

Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors. 

Nilagiri VK, Lee SS-Y, Lingham G, Charng J, Yazar S, Hewitt AW, Griffiths LR, Sanfilippo PG, Tsai T-H, Mackey DA. Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors. Translational Vision Science & Technology. 2023;12(8):14 

 

Changes in Refractive Error During Young Adulthood: The Effects of Longitudinal Screen Time, Ocular Sun Exposure, and Genetic Predisposition 

Lee SS-Y, Lingham G, Wang CA, Diaz Torres S, Pennel CE, Hysi PG, Hammond CJ, Gharahkhani P, Clark R, Guggenheim JA, Mackey DA. Changes in Refractive Error During Young Adulthood: The Effects of Longitudinal Screen Time, Ocular Sun Exposure, and Genetic Predisposition. Invest Ophthalmol Vis Sci. 2023;64(13):28. 

Comparison of cycloplegia at 20- and 30-minutes following proxymetacaine and cyclopentolate instillation in white 12-13-year-olds 

Doyle M, O'Dwyer V, Harrington S. Comparison of cycloplegia at 20- and 30-minutes following proxymetacaine and cyclopentolate instillation in white 12-13-year-olds. 2023;106(8):890-95 

 

Myopia progression patterns among paediatric patients in a clinical setting. Ophthalmic and Physiological Optics. 

Moore M, Lingham G, Flitcroft DI, Loughman J. Myopia progression patterns among paediatric patients in a clinical setting. Ophthalmic and Physiological Optics. 2024. 44 (2), 258-269 

 

The long and short of it: a comprehensive assessment of axial length estimation in myopic eyes from ocular and demographic variables 

Lingham G, Loughman J, Panah DS, Harrington S, Saunders KJ, Ying GS, Cui H, Kobia-Acquah E, Flitcroft DI. The long and short of it: a comprehensive assessment of axial length estimation in myopic eyes from ocular and demographic variables. Eye. 2024. 38 (7), 1333-1341. 

 

Ability to Process Multisensory Information Is Impaired in Open Angle Glaucoma.  

Loskutova E, Butler JS, Setti A, O’Brien C, Loughman J. Ability to Process Multisensory Information Is Impaired in Open Angle Glaucoma. Journal of Glaucoma. 2024 Feb 1;33(2):78-86. 

 

2024 UK and Ireland modified Delphi consensus on myopia management in children and young people. 

Dahlmann‐Noor, A. H., Ghorbani‐Mojarrad, N., Williams, K. M., Ghoneim, A., Allen, P. M., Beach, M. L., ... & Young, A. L. 2024 UK and Ireland modified Delphi consensus on myopia management in children and young people. Ophthalmic and Physiological Optics. 2024. https://doi.org/10.1111/opo.13381 

 

Raman spectroscopic analysis of human blood serum of glaucoma patients supplemented with macular pigment carotenoids 

Udensi, J., Loskutova, E., Loughman, J., & Byrne, H. J. (2024). Raman spectroscopic analysis of human blood serum of glaucoma patients supplemented with macular pigment carotenoids. Journal of biophotonics, 2024. 17(8), e202400060. 

 

Myopia outcome study of atropine in children: two‐year result of daily 0.01% atropine in a European population 

Loughman J, Kobia‐Acquah E, Lingham G, Butler J, Loskutova E, Mackey DA, Lee SS, Flitcroft DI. Myopia outcome study of atropine in children: two‐year result of daily 0.01% atropine in a European population. Acta Ophthalmologica. 2024 (May), e245-256.  

 

Short-term effects of cyclopentolate and tropicamide eye drops on macular choroidal thickness in myopic children 

Kobia-Acquah E, Flitcroft DI, Lingham G, Kerin E, Loughman J. Short-term effects of cyclopentolate and tropicamide eye drops on macular choroidal thickness in myopic children. Ophthalmic & Physiological optics. 2024. 44 (2), 280-291