Publications

Selected recent publications 

• • Baby, E.K., Savitha, R., Kinsella, G.K., Ryan, B.J., Nolan, K., Henehan, G.T. (2025). Structural and mechanistic insights into activators of alcohol dehydrogenase. International Journal of Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2025.148040

  • Savitha, R., Baby, E.K., Kinsella, G.K., Nolan, K., Ryan, B.J., Henehan, G.T. (2025). Extraordinary activation of CALB by alkylammonium ions: a new paradigm for activity enhancement for enzymes. bioRxiv, https://doi.org/10.1101/2025.04.18.649601

  • Baby, E.K., Savitha, R., Kinsella, G.K., Nolan, K., Ryan, B.J., Henehan, G.T. (2025). Novel alcohol dehydrogenase activation by the choline component of Deep Eutectic Solvents. Journal of Molecular Liquids, 423, 127025. https://doi.org/10.1016/j.molliq.2025.127025
  • Akram, M. M., Savitha, R., Kinsella, G.K., Nolan, K., Ryan, B.J., Henehan, G.T. (2024). Microbial and enzymatic biodegradation of plastic waste for a circular economy. Applied Sciences, 4, 11942-11969.
  • Baby, E.K., Savitha, R., Kinsella, G.K., Nolan, K., Ryan, B.J. & Henehan, G.T. (2024). Influence of deep eutectic solvents on redox biocatalysis involving alcohol dehydrogenases. Heliyon, 10(12), e32550. https://doi.org/10.1016/j.heliyon.2024.e32550.
    
  • Tan, Y., Kinsella G.K., Henehan G.T., Ryan B.J. (2022). Listeria monocytogenes is a solvent tolerant organism secreting a solvent stable lipase: potential biotechnological applications. Biotechnology Letters, https://doi.org/10.1007/s10529-022-03284-5.
  • Tan, Y., Kinsella G.K., Henehan G.T., Ryan B.J. (2022). ​​Extracellular secretion of a cutinase with polyester‐degrading potential by E. coli using a novel signal peptide from Amycolatopsis mediterranei. World Journal of Microbiology and Biotechnology,  38, Art. 60. DOI: 10.1007/s11274-022-03246-z.
  • Tan, Y., Kinsella G.K., Henehan G.T., Ryan B.J. (2021). Cutinase from Amycolatopsis mediterannei: Marked activation and stabilisation in Deep Eutectic Solvents. Bioresource Technology Reports, 16. https://doi.org/10.1016/j.biteb.2021.100882
  • Uhoraningoga, A., Kinsella, G.K., Henehan, G.T., Ryan, B.J. (2021). β-glucosidase from Streptomyces griseus: Ester hydrolysis and alkyl glucoside synthesis in the presence of deep eutectic solvents. Current Research in Green and Sustainable Chemistry, 4,  100129 (https://doi.org/10.1016/j.crgsc.2021.100129).
  • Ahmed, W.H., Boulet, N., Briot, A., Ryan B.J., Kinsella, G.K., O'Sullivan, J., Les, F., Mercader-Barceló, J., Henehan G.T., Carpéné, C. (2021). Novel facet for an old dietary molecule? Direct influence of caffeine on glucose and biogenic amine handling by human adipocytes. Molecules, 26, 3831-3850. https://doi.org/10.3390/molecules26133831. 
  • Tan, Y., Kinsella G.K., Henehan G.T., Ryan B.J. (2021). An extracellular lipase from Amycolatopsis mediterannei is a cutinase with plastic degrading activity. Computational and Structural Biotechnology Journal,  19, 869-879.
  • Priyanka P., Kinsella G.K., Henehan G.T., Ryan B.J. (2020). Isolation, purification and characterization of a novel solvent stable lipase from Pseudomonas reinekei. Biocatalysis and Agricultural Biotechnology. 101806. DOI: 10.1016/j.bcab.2020.101806
  • Priyanka, P., Kinsella, G.K., Henehan, G.T., Ryan, B.J. (2020). Nile Red assay development for the estimation of neutral lipids in Chlorella emersonii and Pseudokirchneriella subcapitata. Eurobiotech Journal,  4(4), 216–222.
  • Priyanka, P., Kinsella, G.K., Henehan, G.T., Ryan, B.J. (2020). Enzymatic in-situ transesterification of neutral lipids from simulated wastewater cultured Chlorella emersonii and Pseudokirchneriella subcapitata to sustainably produce Fatty Acid Methyl Esters. Bioresource Technology Reports, 11, https://doi.org/10.1016/ j.biteb.2020.100489.
  • Haj Ahmed, W., Peiro, C., Fontaine, J., Ryan, B.J., Kinsella, G.K., O'Sullivan J., Grolleau J-L., Henehan, G.T.M., Carpéné, C. (2020). Methylxanthines Inhibit Primary Amine Oxidase and Monoamine Oxidase Activities of Human Adipose Tissue. Medicines, 7(4), 18. doi:10.3390/medicines7040018
  • Priyanka, P., Kinsella, G.K., Henehan, G.T., Ryan, B.J. (2019). The Effect of Calcium Alginate Entrapment on the Stability of Novel Lipases from P. Reinekei and P. brenneri. Trends in Protein and Peptide Science, 4, e6:1-10
  • Uhoraningoga, A., Kinsella, G.K., Frias, J.M., Henehan, G.T., Ryan, B.J. (2019). The Statistical Optimisation of Recombinant β-glucosidase Production through a Two-Stage, Multi-Model, Design of Experiments Approach. Bioengineering, 6, 61-84.
  • Priyanka, P., Kinsella, G.K., Henehan, G.T., Ryan, B.J. (2019). Isolation, purification and characterization of a novel solvent stable lipase from Pseudomonas reinekei. Protein Expression and Purification, 153, 121-130.
  • Uhoraningoga, A., Kinsella, G.K., Henehan, G.T., Ryan, B.J. (2018). The Goldilocks Approach; a review of employing Design of Experiments in prokaryotic recombinant protein production. Bioengineering, 5, 89-116.
  • Priyanka, P., Tan, Y., Kinsella, G.K., Henehan, G.T., Ryan, B.J. (2018). Solvent stable microbial lipases: Current understanding and biotechnological applications. Biotechnology Letters, 41, 203-220.
  • Shanahan, P. O'Sullivan J., Tipton, K.F., Kinsella, G., Ryan, B.J. and Henehan, G.T. (2018). Theobromine and related methylxanthines as inhibitors of Primary Amine Oxidase. Food Biochemistry, 43(2):e12697.
  • Shanahan, P. O'Sullivan J., Tipton, K.F., Kinsella, G., Ryan, B.J. and Henehan, G.T. (2017). Dietary phytochemical inhibitors of primary amine oxidase. Journal of Biotechnology, 256, S96-S97.
  • Kumar, P., Ryan, B.J. and Henehan, G.T. (2017). Beta-Glucosidase from Streptomyces griseus: Nanoparticle immobilisation and alkyl glucoside synthesis. Protein Expression and Purification, 132, 164-170.
  • Alka, K., Dolly, O.J., Ryan, B.J., and Henehan, G.T. (2014).  New inhibitors of the KVB2 subunit from the mammalian potassium channels. The International Journal of Biochemistry and Cell Biology, 55, 35-39.
  • Alka, K., Cornally, D., Ryan B.J., Windle, H.J. and Henehan, G.T. (2013). A Short Chain NAD(H)-Dependent Alcohol dehydrogenase (HpSCADH) from Helicobacter pylori: A role in growth under neutral and acidic conditions. The International Journal of Biochemistry & Cell Biology, 45, 1347-1355.